{
  "url": "https://dantelabs.com/traits/myokymia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "myokymia",
    "id": "HP:0002411",
    "name": "Myokymia",
    "definition": "Myokymia consists of involuntary, fine, continuous, undulating contractions that spread across the affected striated muscle.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-movement",
        "name": "Abnormality of movement",
        "url": "https://dantelabs.com/traits/abnormality-of-movement"
      }
    ],
    "narrower": [
      {
        "slug": "facial-myokymia",
        "name": "Involuntary facial quivering",
        "genes": 8,
        "url": "https://dantelabs.com/traits/facial-myokymia"
      },
      {
        "slug": "emg-myokymic-discharges",
        "name": "EMG: myokymic discharges",
        "genes": 2,
        "url": "https://dantelabs.com/traits/emg-myokymic-discharges"
      },
      {
        "slug": "eyelid-myokymia",
        "name": "Eyelid myokymia",
        "genes": 1,
        "url": "https://dantelabs.com/traits/eyelid-myokymia"
      }
    ],
    "genes": [
      {
        "slug": "itpr1",
        "symbol": "ITPR1",
        "hgnc": "HGNC:6180",
        "name": "inositol 1,4,5-trisphosphate receptor type 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itpr1"
      },
      {
        "slug": "sod1",
        "symbol": "SOD1",
        "hgnc": "HGNC:11179",
        "name": "superoxide dismutase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sod1"
      },
      {
        "slug": "hint1",
        "symbol": "HINT1",
        "hgnc": "HGNC:4912",
        "name": "histidine triad nucleotide binding protein 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hint1"
      },
      {
        "slug": "kcna1",
        "symbol": "KCNA1",
        "hgnc": "HGNC:6218",
        "name": "potassium voltage-gated channel subfamily A member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcna1"
      },
      {
        "slug": "gsn",
        "symbol": "GSN",
        "hgnc": "HGNC:4620",
        "name": "gelsolin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gsn"
      },
      {
        "slug": "lgi3",
        "symbol": "LGI3",
        "hgnc": "HGNC:18711",
        "name": "leucine rich repeat LGI family member 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lgi3"
      },
      {
        "slug": "uchl1",
        "symbol": "UCHL1",
        "hgnc": "HGNC:12513",
        "name": "ubiquitin C-terminal hydrolase L1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/uchl1"
      },
      {
        "slug": "morc2",
        "symbol": "MORC2",
        "hgnc": "HGNC:23573",
        "name": "MORC family CW-type zinc finger 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/morc2"
      },
      {
        "slug": "kcnq2",
        "symbol": "KCNQ2",
        "hgnc": "HGNC:6296",
        "name": "potassium voltage-gated channel subfamily Q member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnq2"
      },
      {
        "slug": "pnkd",
        "symbol": "PNKD",
        "hgnc": "HGNC:9153",
        "name": "PNKD metallo-beta-lactamase domain containing",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnkd"
      }
    ]
  }
}