{
  "url": "https://dantelabs.com/traits/mandibular-pain",
  "trait": {
    "bundleId": "2026.10.18-8b139e39",
    "release": "2026-09-01",
    "slug": "mandibular-pain",
    "id": "HP:0200025",
    "name": "Lower jaw pain",
    "label": "Mandibular pain",
    "definition": "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the mandible.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      },
      {
        "slug": "constitutional-symptom",
        "name": "Constitutional symptom",
        "url": "https://dantelabs.com/traits/constitutional-symptom"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-mandible-morphology",
        "name": "Abnormality of the lower jaw bone",
        "url": "https://dantelabs.com/traits/abnormal-mandible-morphology"
      },
      {
        "slug": "pain",
        "name": "Pain",
        "url": "https://dantelabs.com/traits/pain"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cdc73",
        "symbol": "CDC73",
        "hgnc": "HGNC:16783",
        "name": "cell division cycle 73",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdc73"
      },
      {
        "slug": "lrp5",
        "symbol": "LRP5",
        "hgnc": "HGNC:6697",
        "name": "LDL receptor related protein 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp5"
      },
      {
        "slug": "scn9a",
        "symbol": "SCN9A",
        "hgnc": "HGNC:10597",
        "name": "sodium voltage-gated channel alpha subunit 9",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn9a"
      }
    ]
  }
}