{
  "url": "https://dantelabs.com/traits/hypoleucinemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypoleucinemia",
    "id": "HP:0500143",
    "name": "Decreased blood concentration of leucine",
    "label": "Hypoleucinemia",
    "definition": "The concentration of leucine in the blood circulation is below the lower limit of normal.",
    "synonyms": [
      "Low blood leucine levels",
      "Decreased leucine concentration",
      "Decreased leucine level",
      "Decreased leucine level in blood",
      "Reduced leucine concentration",
      "Reduced leucine level",
      "Reduced leucine level in blood"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-leucine-concentration",
        "name": "Abnormal circulating leucine concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-leucine-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "bckdk",
        "symbol": "BCKDK",
        "hgnc": "HGNC:16902",
        "name": "branched chain keto acid dehydrogenase kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bckdk"
      }
    ]
  }
}