{
  "url": "https://dantelabs.com/traits/generalized-arterial-calcification",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "generalized-arterial-calcification",
    "id": "HP:0004940",
    "name": "Generalized arterial calcification",
    "definition": "Calcification, that is, pathological deposition of calcium salts, affecting arteries distributed throughout the body.",
    "synonyms": [
      "Generalised arterial calcification"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "arterial-calcification",
        "name": "Arterial calcification",
        "url": "https://dantelabs.com/traits/arterial-calcification"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "abcc6",
        "symbol": "ABCC6",
        "hgnc": "HGNC:57",
        "name": "ATP binding cassette subfamily C member 6",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/abcc6"
      },
      {
        "slug": "enpp1",
        "symbol": "ENPP1",
        "hgnc": "HGNC:3356",
        "name": "ectonucleotide pyrophosphatase/phosphodiesterase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/enpp1"
      }
    ]
  }
}