{
  "url": "https://dantelabs.com/traits/erysipelas",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "erysipelas",
    "id": "HP:0001055",
    "name": "Erysipelas",
    "definition": "Increased susceptibility to erysipelas, as manifested by a medical history of repeated episodes of erysipelas, which is a superficial infection of the skin, typically involving the lymphatic system.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "inflammatory-abnormality-of-the-skin",
        "name": "Inflammatory abnormality of the skin",
        "url": "https://dantelabs.com/traits/inflammatory-abnormality-of-the-skin"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "mefv",
        "symbol": "MEFV",
        "hgnc": "HGNC:6998",
        "name": "MEFV innate immunity regulator, pyrin",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/mefv"
      },
      {
        "slug": "tnfrsf1a",
        "symbol": "TNFRSF1A",
        "hgnc": "HGNC:11916",
        "name": "TNF receptor superfamily member 1A",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tnfrsf1a"
      },
      {
        "slug": "adamts3",
        "symbol": "ADAMTS3",
        "hgnc": "HGNC:219",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamts3"
      },
      {
        "slug": "ccbe1",
        "symbol": "CCBE1",
        "hgnc": "HGNC:29426",
        "name": "collagen and calcium binding EGF domains 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ccbe1"
      },
      {
        "slug": "fat4",
        "symbol": "FAT4",
        "hgnc": "HGNC:23109",
        "name": "FAT atypical cadherin 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fat4"
      },
      {
        "slug": "fam111b",
        "symbol": "FAM111B",
        "hgnc": "HGNC:24200",
        "name": "FAM111 trypsin like peptidase B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fam111b"
      },
      {
        "slug": "kif11",
        "symbol": "KIF11",
        "hgnc": "HGNC:6388",
        "name": "kinesin family member 11",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif11"
      },
      {
        "slug": "flt4",
        "symbol": "FLT4",
        "hgnc": "HGNC:3767",
        "name": "fms related receptor tyrosine kinase 4",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flt4"
      }
    ]
  }
}