{
  "url": "https://dantelabs.com/traits/cystinuria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cystinuria",
    "id": "HP:0003131",
    "name": "High urine cystine levels",
    "label": "Cystinuria",
    "definition": "An increased concentration of cystine in the urine.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "increased-sulfur-amino-acid-level-in-urine",
        "name": "Increased sulfur amino acid level in urine",
        "url": "https://dantelabs.com/traits/increased-sulfur-amino-acid-level-in-urine"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "camkmt",
        "symbol": "CAMKMT",
        "hgnc": "HGNC:26276",
        "name": "calmodulin-lysine N-methyltransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/camkmt"
      },
      {
        "slug": "ppm1b",
        "symbol": "PPM1B",
        "hgnc": "HGNC:9276",
        "name": "protein phosphatase, Mg2+/Mn2+ dependent 1B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppm1b"
      },
      {
        "slug": "prepl",
        "symbol": "PREPL",
        "hgnc": "HGNC:30228",
        "name": "prolyl endopeptidase like",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prepl"
      },
      {
        "slug": "slc3a1",
        "symbol": "SLC3A1",
        "hgnc": "HGNC:11025",
        "name": "solute carrier family 3 member 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/slc3a1"
      },
      {
        "slug": "aass",
        "symbol": "AASS",
        "hgnc": "HGNC:17366",
        "name": "aminoadipate-semialdehyde synthase",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/aass"
      },
      {
        "slug": "slc7a9",
        "symbol": "SLC7A9",
        "hgnc": "HGNC:11067",
        "name": "solute carrier family 7 member 9",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc7a9"
      }
    ]
  }
}