{
  "url": "https://dantelabs.com/traits/congenital-megaureter",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "congenital-megaureter",
    "id": "HP:0008676",
    "name": "Congenital megaureter",
    "definition": "A developmental disturbance with extreme ureteral dilatation.",
    "synonyms": [
      "Congenital megaloureter",
      "Primary megaloureter",
      "Primary megaureter"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "hydroureter",
        "name": "Hydroureter",
        "url": "https://dantelabs.com/traits/hydroureter"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "med16",
        "symbol": "MED16",
        "hgnc": "HGNC:17556",
        "name": "mediator complex subunit 16",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/med16"
      },
      {
        "slug": "pigt",
        "symbol": "PIGT",
        "hgnc": "HGNC:14938",
        "name": "phosphatidylinositol glycan anchor biosynthesis class T",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigt"
      },
      {
        "slug": "pign",
        "symbol": "PIGN",
        "hgnc": "HGNC:8967",
        "name": "phosphatidylinositol glycan anchor biosynthesis class N",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pign"
      },
      {
        "slug": "tbx18",
        "symbol": "TBX18",
        "hgnc": "HGNC:11595",
        "name": "T-box transcription factor 18",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx18"
      }
    ]
  }
}