{
  "url": "https://dantelabs.com/traits/broad-metatarsal",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "broad-metatarsal",
    "id": "HP:0001783",
    "name": "Wide long bone of foot",
    "label": "Broad metatarsal",
    "definition": "Increased side-to-side width of a metatarsal bone.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-metatarsal-morphology",
        "name": "Abnormality of the long bone of foot",
        "url": "https://dantelabs.com/traits/abnormal-metatarsal-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "broad-first-metatarsal",
        "name": "Wide 1st long bone of foot",
        "genes": 6,
        "url": "https://dantelabs.com/traits/broad-first-metatarsal"
      }
    ],
    "genes": [
      {
        "slug": "mmp2",
        "symbol": "MMP2",
        "hgnc": "HGNC:7166",
        "name": "matrix metallopeptidase 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmp2"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "rab33b",
        "symbol": "RAB33B",
        "hgnc": "HGNC:16075",
        "name": "RAB33B, member RAS oncogene family",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab33b"
      },
      {
        "slug": "fgfr2",
        "symbol": "FGFR2",
        "hgnc": "HGNC:3689",
        "name": "fibroblast growth factor receptor 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fgfr2"
      },
      {
        "slug": "pde4d",
        "symbol": "PDE4D",
        "hgnc": "HGNC:8783",
        "name": "phosphodiesterase 4D",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde4d"
      },
      {
        "slug": "adamts10",
        "symbol": "ADAMTS10",
        "hgnc": "HGNC:13201",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 10",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamts10"
      },
      {
        "slug": "fbn1",
        "symbol": "FBN1",
        "hgnc": "HGNC:3603",
        "name": "fibrillin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbn1"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "npr2",
        "symbol": "NPR2",
        "hgnc": "HGNC:7944",
        "name": "natriuretic peptide receptor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npr2"
      }
    ]
  }
}