{
  "url": "https://dantelabs.com/traits/bacterial-meningitis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "bacterial-meningitis",
    "id": "HP:5210217",
    "name": "Bacterial meningitis",
    "definition": "A meningitis caused by bacterial infection, with common causative organisms including Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type b. A recurrent or invasive bacterial meningitis with encapsulated organisms can be a manifestation of unusual susceptibility to infection, particularly in antibody deficiencies, complement deficiencies, and asplenia.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "meningitis",
        "name": "Meningitis",
        "url": "https://dantelabs.com/traits/meningitis"
      },
      {
        "slug": "unusual-bacterial-infection",
        "name": "Unusual bacterial infection",
        "url": "https://dantelabs.com/traits/unusual-bacterial-infection"
      }
    ],
    "narrower": [
      {
        "slug": "recurrent-bacterial-meningitis",
        "name": "Recurrent bacterial meningitis",
        "genes": 3,
        "url": "https://dantelabs.com/traits/recurrent-bacterial-meningitis"
      }
    ],
    "genes": [
      {
        "slug": "ikbkg",
        "symbol": "IKBKG",
        "hgnc": "HGNC:5961",
        "name": "inhibitor of nuclear factor kappa B kinase regulatory subunit gamma",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ikbkg"
      }
    ]
  }
}