{
  "url": "https://dantelabs.com/traits/azoospermia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "azoospermia",
    "id": "HP:0000027",
    "name": "Absent sperm in semen",
    "label": "Azoospermia",
    "definition": "Absence of any measurable level of sperm,whereby spermatozoa cannot be observed even after centrifugation of the semen pellet.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-spermatogenesis",
        "name": "Abnormal sperm development",
        "url": "https://dantelabs.com/traits/abnormal-spermatogenesis"
      }
    ],
    "narrower": [
      {
        "slug": "non-obstructive-azoospermia",
        "name": "Non-obstructive azoospermia",
        "genes": 69,
        "url": "https://dantelabs.com/traits/non-obstructive-azoospermia"
      },
      {
        "slug": "obstructive-azoospermia",
        "name": "Obstructive azoospermia",
        "genes": 39,
        "url": "https://dantelabs.com/traits/obstructive-azoospermia"
      }
    ],
    "genes": [
      {
        "slug": "c14orf39",
        "symbol": "C14orf39",
        "hgnc": "HGNC:19849",
        "name": "chromosome 14 open reading frame 39",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c14orf39"
      },
      {
        "slug": "dcaf17",
        "symbol": "DCAF17",
        "hgnc": "HGNC:25784",
        "name": "DDB1 and CUL4 associated factor 17",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dcaf17"
      },
      {
        "slug": "dnah9",
        "symbol": "DNAH9",
        "hgnc": "HGNC:2953",
        "name": "dynein axonemal heavy chain 9",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnah9"
      },
      {
        "slug": "lhb",
        "symbol": "LHB",
        "hgnc": "HGNC:6584",
        "name": "luteinizing hormone subunit beta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhb"
      },
      {
        "slug": "m1ap",
        "symbol": "M1AP",
        "hgnc": "HGNC:25183",
        "name": "meiosis 1 associated protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/m1ap"
      },
      {
        "slug": "scp2",
        "symbol": "SCP2",
        "hgnc": "HGNC:10606",
        "name": "sterol carrier protein 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scp2"
      },
      {
        "slug": "slc29a3",
        "symbol": "SLC29A3",
        "hgnc": "HGNC:23096",
        "name": "solute carrier family 29 member 3",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc29a3"
      },
      {
        "slug": "sox9",
        "symbol": "SOX9",
        "hgnc": "HGNC:11204",
        "name": "SRY-box transcription factor 9",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sox9"
      },
      {
        "slug": "steap3",
        "symbol": "STEAP3",
        "hgnc": "HGNC:24592",
        "name": "STEAP3 metalloreductase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/steap3"
      },
      {
        "slug": "sycp3",
        "symbol": "SYCP3",
        "hgnc": "HGNC:18130",
        "name": "synaptonemal complex protein 3",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sycp3"
      },
      {
        "slug": "tex11",
        "symbol": "TEX11",
        "hgnc": "HGNC:11733",
        "name": "testis expressed 11",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tex11"
      },
      {
        "slug": "tex14",
        "symbol": "TEX14",
        "hgnc": "HGNC:11737",
        "name": "testis expressed 14, intercellular bridge forming factor",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tex14"
      },
      {
        "slug": "xrcc2",
        "symbol": "XRCC2",
        "hgnc": "HGNC:12829",
        "name": "X-ray repair cross complementing 2",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/xrcc2"
      },
      {
        "slug": "zmynd15",
        "symbol": "ZMYND15",
        "hgnc": "HGNC:20997",
        "name": "zinc finger MYND-type containing 15",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/zmynd15"
      },
      {
        "slug": "catip",
        "symbol": "CATIP",
        "hgnc": "HGNC:25062",
        "name": "ciliogenesis associated TTC17 interacting protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/catip"
      },
      {
        "slug": "catsper2",
        "symbol": "CATSPER2",
        "hgnc": "HGNC:18810",
        "name": "cation channel sperm associated 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/catsper2"
      },
      {
        "slug": "ccdc34",
        "symbol": "CCDC34",
        "hgnc": "HGNC:25079",
        "name": "coiled-coil domain containing 34",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc34"
      },
      {
        "slug": "cftr",
        "symbol": "CFTR",
        "hgnc": "HGNC:1884",
        "name": "CF transmembrane conductance regulator",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cftr"
      },
      {
        "slug": "chd7",
        "symbol": "CHD7",
        "hgnc": "HGNC:20626",
        "name": "chromodomain helicase DNA binding protein 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd7"
      },
      {
        "slug": "ct55",
        "symbol": "CT55",
        "hgnc": "HGNC:26047",
        "name": "cancer/testis antigen 55",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ct55"
      },
      {
        "slug": "dhx37",
        "symbol": "DHX37",
        "hgnc": "HGNC:17210",
        "name": "DEAH-box helicase 37",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx37"
      },
      {
        "slug": "dnah10",
        "symbol": "DNAH10",
        "hgnc": "HGNC:2941",
        "name": "dynein axonemal heavy chain 10",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnah10"
      },
      {
        "slug": "dnhd1",
        "symbol": "DNHD1",
        "hgnc": "HGNC:26532",
        "name": "dynein heavy chain domain 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnhd1"
      },
      {
        "slug": "dusp6",
        "symbol": "DUSP6",
        "hgnc": "HGNC:3072",
        "name": "dual specificity phosphatase 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dusp6"
      },
      {
        "slug": "emx2",
        "symbol": "EMX2",
        "hgnc": "HGNC:3341",
        "name": "empty spiracles homeobox 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/emx2"
      },
      {
        "slug": "fancm",
        "symbol": "FANCM",
        "hgnc": "HGNC:23168",
        "name": "FA complementation group M",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fancm"
      },
      {
        "slug": "fbxo43",
        "symbol": "FBXO43",
        "hgnc": "HGNC:28521",
        "name": "F-box protein 43",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo43"
      },
      {
        "slug": "fgf17",
        "symbol": "FGF17",
        "hgnc": "HGNC:3673",
        "name": "fibroblast growth factor 17",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf17"
      },
      {
        "slug": "fgf8",
        "symbol": "FGF8",
        "hgnc": "HGNC:3686",
        "name": "fibroblast growth factor 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf8"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "gata4",
        "symbol": "GATA4",
        "hgnc": "HGNC:4173",
        "name": "GATA binding protein 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gata4"
      },
      {
        "slug": "gcna",
        "symbol": "GCNA",
        "hgnc": "HGNC:15805",
        "name": "germ cell nuclear acidic peptidase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gcna"
      },
      {
        "slug": "gnrh1",
        "symbol": "GNRH1",
        "hgnc": "HGNC:4419",
        "name": "gonadotropin releasing hormone 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnrh1"
      },
      {
        "slug": "gnrhr",
        "symbol": "GNRHR",
        "hgnc": "HGNC:4421",
        "name": "gonadotropin releasing hormone receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnrhr"
      },
      {
        "slug": "hnf1b",
        "symbol": "HNF1B",
        "hgnc": "HGNC:11630",
        "name": "HNF1 homeobox B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hnf1b"
      },
      {
        "slug": "hs6st1",
        "symbol": "HS6ST1",
        "hgnc": "HGNC:5201",
        "name": "heparan sulfate 6-O-sulfotransferase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hs6st1"
      },
      {
        "slug": "kiss1",
        "symbol": "KISS1",
        "hgnc": "HGNC:6341",
        "name": "KiSS-1 metastasis suppressor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiss1"
      },
      {
        "slug": "kiss1r",
        "symbol": "KISS1R",
        "hgnc": "HGNC:4510",
        "name": "KISS1 receptor",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kiss1r"
      },
      {
        "slug": "klhl10",
        "symbol": "KLHL10",
        "hgnc": "HGNC:18829",
        "name": "kelch like family member 10",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl10"
      },
      {
        "slug": "map3k1",
        "symbol": "MAP3K1",
        "hgnc": "HGNC:6848",
        "name": "mitogen-activated protein kinase kinase kinase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map3k1"
      },
      {
        "slug": "meiob",
        "symbol": "MEIOB",
        "hgnc": "HGNC:28569",
        "name": "meiosis specific with OB-fold",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/meiob"
      },
      {
        "slug": "mov10l1",
        "symbol": "MOV10L1",
        "hgnc": "HGNC:7201",
        "name": "Mov10 like RNA helicase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mov10l1"
      },
      {
        "slug": "msh5",
        "symbol": "MSH5",
        "hgnc": "HGNC:7328",
        "name": "mutS homolog 5",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msh5"
      },
      {
        "slug": "nanos1",
        "symbol": "NANOS1",
        "hgnc": "HGNC:23044",
        "name": "nanos C2HC-type zinc finger 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nanos1"
      },
      {
        "slug": "nhlh2",
        "symbol": "NHLH2",
        "hgnc": "HGNC:7818",
        "name": "nescient helix-loop-helix 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nhlh2"
      },
      {
        "slug": "nr0b1",
        "symbol": "NR0B1",
        "hgnc": "HGNC:7960",
        "name": "nuclear receptor subfamily 0 group B member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nr0b1"
      },
      {
        "slug": "nr5a1",
        "symbol": "NR5A1",
        "hgnc": "HGNC:7983",
        "name": "nuclear receptor subfamily 5 group A member 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/nr5a1"
      },
      {
        "slug": "nsmf",
        "symbol": "NSMF",
        "hgnc": "HGNC:29843",
        "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsmf"
      },
      {
        "slug": "pdha2",
        "symbol": "PDHA2",
        "hgnc": "HGNC:8807",
        "name": "pyruvate dehydrogenase E1 subunit alpha 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pdha2"
      },
      {
        "slug": "pnldc1",
        "symbol": "PNLDC1",
        "hgnc": "HGNC:21185",
        "name": "PARN like ribonuclease domain containing exonuclease 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnldc1"
      },
      {
        "slug": "prok2",
        "symbol": "PROK2",
        "hgnc": "HGNC:18455",
        "name": "prokineticin 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prok2"
      },
      {
        "slug": "prokr2",
        "symbol": "PROKR2",
        "hgnc": "HGNC:15836",
        "name": "prokineticin receptor 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prokr2"
      },
      {
        "slug": "rbbp7",
        "symbol": "RBBP7",
        "hgnc": "HGNC:9890",
        "name": "RB binding protein 7, chromatin remodeling factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbbp7"
      },
      {
        "slug": "rnf212",
        "symbol": "RNF212",
        "hgnc": "HGNC:27729",
        "name": "ring finger protein 212",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf212"
      },
      {
        "slug": "rpl10l",
        "symbol": "RPL10L",
        "hgnc": "HGNC:17976",
        "name": "ribosomal protein L10 like",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl10l"
      },
      {
        "slug": "shoc1",
        "symbol": "SHOC1",
        "hgnc": "HGNC:26535",
        "name": "shortage in chiasmata 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/shoc1"
      },
      {
        "slug": "sohlh1",
        "symbol": "SOHLH1",
        "hgnc": "HGNC:27845",
        "name": "spermatogenesis and oogenesis specific basic helix-loop-helix 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sohlh1"
      },
      {
        "slug": "spag17",
        "symbol": "SPAG17",
        "hgnc": "HGNC:26620",
        "name": "sperm associated antigen 17",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spag17"
      },
      {
        "slug": "spink2",
        "symbol": "SPINK2",
        "hgnc": "HGNC:11245",
        "name": "serine peptidase inhibitor Kazal type 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spink2"
      },
      {
        "slug": "spry4",
        "symbol": "SPRY4",
        "hgnc": "HGNC:15533",
        "name": "sprouty RTK signaling antagonist 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spry4"
      },
      {
        "slug": "sry",
        "symbol": "SRY",
        "hgnc": "HGNC:11311",
        "name": "sex determining region Y",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/sry"
      },
      {
        "slug": "stag3",
        "symbol": "STAG3",
        "hgnc": "HGNC:11356",
        "name": "STAG3 cohesin complex component",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stag3"
      },
      {
        "slug": "strc",
        "symbol": "STRC",
        "hgnc": "HGNC:16035",
        "name": "stereocilin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/strc"
      },
      {
        "slug": "syce1",
        "symbol": "SYCE1",
        "hgnc": "HGNC:28852",
        "name": "synaptonemal complex central element protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/syce1"
      },
      {
        "slug": "tac3",
        "symbol": "TAC3",
        "hgnc": "HGNC:11521",
        "name": "tachykinin precursor 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tac3"
      },
      {
        "slug": "tacr3",
        "symbol": "TACR3",
        "hgnc": "HGNC:11528",
        "name": "tachykinin receptor 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tacr3"
      },
      {
        "slug": "taf4b",
        "symbol": "TAF4B",
        "hgnc": "HGNC:11538",
        "name": "TATA-box binding protein associated factor 4b",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/taf4b"
      },
      {
        "slug": "tdrd9",
        "symbol": "TDRD9",
        "hgnc": "HGNC:20122",
        "name": "tudor domain containing 9",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tdrd9"
      },
      {
        "slug": "terb1",
        "symbol": "TERB1",
        "hgnc": "HGNC:26675",
        "name": "telomere repeat binding bouquet formation protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/terb1"
      },
      {
        "slug": "terb2",
        "symbol": "TERB2",
        "hgnc": "HGNC:28520",
        "name": "telomere repeat binding bouquet formation protein 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/terb2"
      },
      {
        "slug": "tex15",
        "symbol": "TEX15",
        "hgnc": "HGNC:11738",
        "name": "testis expressed 15, meiosis and synapsis associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tex15"
      },
      {
        "slug": "vamp7",
        "symbol": "VAMP7",
        "hgnc": "HGNC:11486",
        "name": "vesicle associated membrane protein 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vamp7"
      },
      {
        "slug": "wdr11",
        "symbol": "WDR11",
        "hgnc": "HGNC:13831",
        "name": "WD repeat domain 11",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr11"
      },
      {
        "slug": "wnt4",
        "symbol": "WNT4",
        "hgnc": "HGNC:12783",
        "name": "Wnt family member 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnt4"
      },
      {
        "slug": "wt1",
        "symbol": "WT1",
        "hgnc": "HGNC:12796",
        "name": "WT1 transcription factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wt1"
      },
      {
        "slug": "wwox",
        "symbol": "WWOX",
        "hgnc": "HGNC:12799",
        "name": "WW domain containing oxidoreductase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wwox"
      },
      {
        "slug": "zfpm2",
        "symbol": "ZFPM2",
        "hgnc": "HGNC:16700",
        "name": "zinc finger protein, FOG family member 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfpm2"
      },
      {
        "slug": "zswim7",
        "symbol": "ZSWIM7",
        "hgnc": "HGNC:26993",
        "name": "zinc finger SWIM-type containing 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zswim7"
      },
      {
        "slug": "ank1",
        "symbol": "ANK1",
        "hgnc": "HGNC:492",
        "name": "ankyrin 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ank1"
      },
      {
        "slug": "brcc3",
        "symbol": "BRCC3",
        "hgnc": "HGNC:24185",
        "name": "BRCA1/BRCA2-containing complex subunit 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brcc3"
      },
      {
        "slug": "fshb",
        "symbol": "FSHB",
        "hgnc": "HGNC:3964",
        "name": "follicle stimulating hormone subunit beta",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fshb"
      },
      {
        "slug": "ar",
        "symbol": "AR",
        "hgnc": "HGNC:644",
        "name": "androgen receptor",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ar"
      },
      {
        "slug": "blm",
        "symbol": "BLM",
        "hgnc": "HGNC:1058",
        "name": "BLM RecQ like helicase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/blm"
      },
      {
        "slug": "brca1",
        "symbol": "BRCA1",
        "hgnc": "HGNC:1100",
        "name": "BRCA1 DNA repair associated",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca1"
      },
      {
        "slug": "brca2",
        "symbol": "BRCA2",
        "hgnc": "HGNC:1101",
        "name": "BRCA2 DNA repair associated",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca2"
      },
      {
        "slug": "brip1",
        "symbol": "BRIP1",
        "hgnc": "HGNC:20473",
        "name": "BRCA1 interacting DNA helicase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brip1"
      },
      {
        "slug": "cfap57",
        "symbol": "CFAP57",
        "hgnc": "HGNC:26485",
        "name": "cilia and flagella associated protein 57",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap57"
      },
      {
        "slug": "ercc4",
        "symbol": "ERCC4",
        "hgnc": "HGNC:3436",
        "name": "ERCC excision repair 4, endonuclease catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc4"
      },
      {
        "slug": "faap100",
        "symbol": "FAAP100",
        "hgnc": "HGNC:26171",
        "name": "FA core complex associated protein 100",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/faap100"
      },
      {
        "slug": "fanca",
        "symbol": "FANCA",
        "hgnc": "HGNC:3582",
        "name": "FA complementation group A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fanca"
      },
      {
        "slug": "fancb",
        "symbol": "FANCB",
        "hgnc": "HGNC:3583",
        "name": "FA complementation group B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancb"
      },
      {
        "slug": "fancc",
        "symbol": "FANCC",
        "hgnc": "HGNC:3584",
        "name": "FA complementation group C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancc"
      },
      {
        "slug": "fancd2",
        "symbol": "FANCD2",
        "hgnc": "HGNC:3585",
        "name": "FA complementation group D2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancd2"
      },
      {
        "slug": "fance",
        "symbol": "FANCE",
        "hgnc": "HGNC:3586",
        "name": "FA complementation group E",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fance"
      },
      {
        "slug": "fancf",
        "symbol": "FANCF",
        "hgnc": "HGNC:3587",
        "name": "FA complementation group F",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancf"
      },
      {
        "slug": "fancg",
        "symbol": "FANCG",
        "hgnc": "HGNC:3588",
        "name": "FA complementation group G",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancg"
      },
      {
        "slug": "fanci",
        "symbol": "FANCI",
        "hgnc": "HGNC:25568",
        "name": "FA complementation group I",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fanci"
      },
      {
        "slug": "fancl",
        "symbol": "FANCL",
        "hgnc": "HGNC:20748",
        "name": "FA complementation group L",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fancl"
      },
      {
        "slug": "fkbp6",
        "symbol": "FKBP6",
        "hgnc": "HGNC:3722",
        "name": "FKBP prolyl isomerase family member 6 (inactive)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fkbp6"
      },
      {
        "slug": "hsd3b2",
        "symbol": "HSD3B2",
        "hgnc": "HGNC:5218",
        "name": "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hsd3b2"
      },
      {
        "slug": "mad2l2",
        "symbol": "MAD2L2",
        "hgnc": "HGNC:6764",
        "name": "mitotic arrest deficient 2 like 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mad2l2"
      },
      {
        "slug": "ocrl",
        "symbol": "OCRL",
        "hgnc": "HGNC:8108",
        "name": "OCRL inositol polyphosphate-5-phosphatase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ocrl"
      },
      {
        "slug": "palb2",
        "symbol": "PALB2",
        "hgnc": "HGNC:26144",
        "name": "partner and localizer of BRCA2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/palb2"
      },
      {
        "slug": "rad51",
        "symbol": "RAD51",
        "hgnc": "HGNC:9817",
        "name": "RAD51 recombinase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad51"
      },
      {
        "slug": "rad51c",
        "symbol": "RAD51C",
        "hgnc": "HGNC:9820",
        "name": "RAD51 paralog C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rad51c"
      },
      {
        "slug": "rfwd3",
        "symbol": "RFWD3",
        "hgnc": "HGNC:25539",
        "name": "ring finger and WD repeat domain 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfwd3"
      },
      {
        "slug": "slx4",
        "symbol": "SLX4",
        "hgnc": "HGNC:23845",
        "name": "SLX4 structure-specific endonuclease subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slx4"
      },
      {
        "slug": "ube2t",
        "symbol": "UBE2T",
        "hgnc": "HGNC:25009",
        "name": "ubiquitin conjugating enzyme E2 T",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube2t"
      },
      {
        "slug": "gba1",
        "symbol": "GBA1",
        "hgnc": "HGNC:4177",
        "name": "glucosylceramidase beta 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gba1"
      },
      {
        "slug": "mc2r",
        "symbol": "MC2R",
        "hgnc": "HGNC:6930",
        "name": "melanocortin 2 receptor",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mc2r"
      },
      {
        "slug": "mrap",
        "symbol": "MRAP",
        "hgnc": "HGNC:1304",
        "name": "melanocortin 2 receptor accessory protein",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mrap"
      },
      {
        "slug": "nnt",
        "symbol": "NNT",
        "hgnc": "HGNC:7863",
        "name": "nicotinamide nucleotide transhydrogenase",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nnt"
      },
      {
        "slug": "star",
        "symbol": "STAR",
        "hgnc": "HGNC:11359",
        "name": "steroidogenic acute regulatory protein",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/star"
      },
      {
        "slug": "txnrd2",
        "symbol": "TXNRD2",
        "hgnc": "HGNC:18155",
        "name": "thioredoxin reductase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/txnrd2"
      },
      {
        "slug": "adgrg2",
        "symbol": "ADGRG2",
        "hgnc": "HGNC:4516",
        "name": "adhesion G protein-coupled receptor G2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adgrg2"
      },
      {
        "slug": "anos1",
        "symbol": "ANOS1",
        "hgnc": "HGNC:6211",
        "name": "anosmin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/anos1"
      },
      {
        "slug": "bcl10",
        "symbol": "BCL10",
        "hgnc": "HGNC:989",
        "name": "BCL10 immune signaling adaptor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bcl10"
      },
      {
        "slug": "bmp2",
        "symbol": "BMP2",
        "hgnc": "HGNC:1069",
        "name": "bone morphogenetic protein 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bmp2"
      },
      {
        "slug": "bpy2",
        "symbol": "BPY2",
        "hgnc": "HGNC:13508",
        "name": "basic charge Y-linked 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bpy2"
      },
      {
        "slug": "cdy1",
        "symbol": "CDY1",
        "hgnc": "HGNC:1809",
        "name": "chromodomain Y-linked 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdy1"
      },
      {
        "slug": "cdy2a",
        "symbol": "CDY2A",
        "hgnc": "HGNC:1810",
        "name": "chromodomain Y-linked 2A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdy2a"
      },
      {
        "slug": "cep19",
        "symbol": "CEP19",
        "hgnc": "HGNC:28209",
        "name": "centrosomal protein 19",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep19"
      },
      {
        "slug": "cfap221",
        "symbol": "CFAP221",
        "hgnc": "HGNC:33720",
        "name": "cilia and flagella associated protein 221",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap221"
      },
      {
        "slug": "daz1",
        "symbol": "DAZ1",
        "hgnc": "HGNC:2682",
        "name": "deleted in azoospermia 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/daz1"
      },
      {
        "slug": "daz2",
        "symbol": "DAZ2",
        "hgnc": "HGNC:15964",
        "name": "deleted in azoospermia 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/daz2"
      },
      {
        "slug": "daz3",
        "symbol": "DAZ3",
        "hgnc": "HGNC:15965",
        "name": "deleted in azoospermia 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/daz3"
      },
      {
        "slug": "ddx3y",
        "symbol": "DDX3Y",
        "hgnc": "HGNC:2699",
        "name": "DEAD-box helicase 3 Y-linked",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ddx3y"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "hfe",
        "symbol": "HFE",
        "hgnc": "HGNC:4886",
        "name": "homeostatic iron regulator",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hfe"
      },
      {
        "slug": "hjv",
        "symbol": "HJV",
        "hgnc": "HGNC:4887",
        "name": "hemojuvelin BMP co-receptor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hjv"
      },
      {
        "slug": "hsfy1",
        "symbol": "HSFY1",
        "hgnc": "HGNC:18568",
        "name": "heat shock transcription factor Y-linked 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hsfy1"
      },
      {
        "slug": "kdm5d",
        "symbol": "KDM5D",
        "hgnc": "HGNC:11115",
        "name": "lysine demethylase 5D",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdm5d"
      },
      {
        "slug": "kit",
        "symbol": "KIT",
        "hgnc": "HGNC:6342",
        "name": "KIT proto-oncogene, receptor tyrosine kinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kit"
      },
      {
        "slug": "mcm8",
        "symbol": "MCM8",
        "hgnc": "HGNC:16147",
        "name": "minichromosome maintenance 8 homologous recombination repair factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mcm8"
      },
      {
        "slug": "msh4",
        "symbol": "MSH4",
        "hgnc": "HGNC:7327",
        "name": "mutS homolog 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msh4"
      },
      {
        "slug": "pry",
        "symbol": "PRY",
        "hgnc": "HGNC:14024",
        "name": "PTPN13 like Y-linked",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pry"
      },
      {
        "slug": "pry2",
        "symbol": "PRY2",
        "hgnc": "HGNC:21504",
        "name": "PTPN13 like Y-linked 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pry2"
      },
      {
        "slug": "rbmy1a1",
        "symbol": "RBMY1A1",
        "hgnc": "HGNC:9912",
        "name": "RNA binding motif protein Y-linked family 1 member A1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbmy1a1"
      },
      {
        "slug": "rps4y2",
        "symbol": "RPS4Y2",
        "hgnc": "HGNC:18501",
        "name": "ribosomal protein S4 Y-linked 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rps4y2"
      },
      {
        "slug": "sema3a",
        "symbol": "SEMA3A",
        "hgnc": "HGNC:10723",
        "name": "semaphorin 3A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3a"
      },
      {
        "slug": "stk11",
        "symbol": "STK11",
        "hgnc": "HGNC:11389",
        "name": "serine/threonine kinase 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stk11"
      },
      {
        "slug": "usp9y",
        "symbol": "USP9Y",
        "hgnc": "HGNC:12633",
        "name": "ubiquitin specific peptidase 9 Y-linked",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp9y"
      },
      {
        "slug": "vcy",
        "symbol": "VCY",
        "hgnc": "HGNC:12668",
        "name": "variable charge Y-linked",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vcy"
      },
      {
        "slug": "xkry",
        "symbol": "XKRY",
        "hgnc": "HGNC:18571",
        "name": "XK related, Y-linked (pseudogene)",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xkry"
      }
    ]
  }
}