{
  "url": "https://dantelabs.com/traits/amyoplasia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "amyoplasia",
    "id": "HP:0003634",
    "name": "Absent muscles since birth",
    "label": "Amyoplasia",
    "definition": "Congenital lack of development of the muscles, which are then replaced by a mixture of dense fat and fibrous tissue.",
    "synonyms": [
      "Congenital absence of muscles"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "aplasia-of-the-musculature",
        "name": "Absent musculature",
        "url": "https://dantelabs.com/traits/aplasia-of-the-musculature"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "chrna1",
        "symbol": "CHRNA1",
        "hgnc": "HGNC:1955",
        "name": "cholinergic receptor nicotinic alpha 1 subunit",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrna1"
      },
      {
        "slug": "chrnd",
        "symbol": "CHRND",
        "hgnc": "HGNC:1965",
        "name": "cholinergic receptor nicotinic delta subunit",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrnd"
      },
      {
        "slug": "chrng",
        "symbol": "CHRNG",
        "hgnc": "HGNC:1967",
        "name": "cholinergic receptor nicotinic gamma subunit",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrng"
      },
      {
        "slug": "trpv4",
        "symbol": "TRPV4",
        "hgnc": "HGNC:18083",
        "name": "transient receptor potential cation channel subfamily V member 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trpv4"
      }
    ]
  }
}