{
  "url": "https://dantelabs.com/traits/abnormal-epiphysis-morphology",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "abnormal-epiphysis-morphology",
    "id": "HP:0005930",
    "name": "Abnormal shape of end part of bone",
    "label": "Abnormal epiphysis morphology",
    "definition": "An anomaly of epiphysis, which is the expanded articular end of a long bone that developes from a secondary ossification center, and which during the period of growth is either entirely cartilaginous or is separated from the shaft by a cartilaginous disk.",
    "synonyms": [
      "Abnormality of epiphysis morphology",
      "Abnormality of the epiphyses",
      "Anomaly of the epiphyses",
      "Epiphyseal abnormality"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-long-bone-morphology",
        "name": "Abnormal shape of long bone",
        "url": "https://dantelabs.com/traits/abnormal-long-bone-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "cone-shaped-epiphysis",
        "name": "Cone-shaped end part of bone",
        "genes": 66,
        "url": "https://dantelabs.com/traits/cone-shaped-epiphysis"
      },
      {
        "slug": "epiphyseal-stippling",
        "name": "Speckled calcifications in end part of bone",
        "genes": 34,
        "url": "https://dantelabs.com/traits/epiphyseal-stippling"
      },
      {
        "slug": "epiphyseal-dysplasia",
        "name": "Abnormal development of end part of bone",
        "genes": 31,
        "url": "https://dantelabs.com/traits/epiphyseal-dysplasia"
      },
      {
        "slug": "delayed-epiphyseal-ossification",
        "name": "Delayed maturation of end part of long bone",
        "genes": 26,
        "url": "https://dantelabs.com/traits/delayed-epiphyseal-ossification"
      },
      {
        "slug": "small-epiphyses",
        "name": "Small end part of bone",
        "genes": 20,
        "url": "https://dantelabs.com/traits/small-epiphyses"
      },
      {
        "slug": "flattened-epiphysis",
        "name": "Flat end part of bone",
        "genes": 17,
        "url": "https://dantelabs.com/traits/flattened-epiphysis"
      },
      {
        "slug": "irregular-epiphyses",
        "name": "Irregular end part of long bone",
        "genes": 17,
        "url": "https://dantelabs.com/traits/irregular-epiphyses"
      },
      {
        "slug": "enlarged-epiphyses",
        "name": "Large end part of bone",
        "genes": 7,
        "url": "https://dantelabs.com/traits/enlarged-epiphyses"
      },
      {
        "slug": "ivory-epiphyses",
        "name": "Increased bone density in end part of bone",
        "genes": 3,
        "url": "https://dantelabs.com/traits/ivory-epiphyses"
      },
      {
        "slug": "pseudoepiphyses",
        "name": "Pseudoepiphyses",
        "genes": 3,
        "url": "https://dantelabs.com/traits/pseudoepiphyses"
      },
      {
        "slug": "abnormal-vertebral-epiphysis-morphology",
        "name": "Abnormal shape of the end part of the vertebra bone",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-vertebral-epiphysis-morphology"
      },
      {
        "slug": "epiphyseal-deformities-of-tubular-bones",
        "name": "Epiphyseal deformities of tubular bones",
        "genes": 2,
        "url": "https://dantelabs.com/traits/epiphyseal-deformities-of-tubular-bones"
      },
      {
        "slug": "fragmented-epiphyses",
        "name": "Fragmented end part of bone",
        "genes": 2,
        "url": "https://dantelabs.com/traits/fragmented-epiphyses"
      },
      {
        "slug": "absent-epiphyses",
        "name": "Absent end part of bone",
        "genes": 1,
        "url": "https://dantelabs.com/traits/absent-epiphyses"
      },
      {
        "slug": "multinucleated-giant-chondrocytes-in-epiphyseal-cartilage",
        "name": "Multinucleated giant chondrocytes in epiphyseal cartilage",
        "genes": 1,
        "url": "https://dantelabs.com/traits/multinucleated-giant-chondrocytes-in-epiphyseal-cartilage"
      },
      {
        "slug": "splayed-epiphyses",
        "name": "Splayed end part of bone",
        "genes": 1,
        "url": "https://dantelabs.com/traits/splayed-epiphyses"
      },
      {
        "slug": "abnormal-limb-epiphysis-morphology",
        "name": "Abnormal shape of end part of limb bones",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-limb-epiphysis-morphology"
      },
      {
        "slug": "triangular-epiphysis",
        "name": "Triangular end part of bone",
        "genes": 0,
        "url": "https://dantelabs.com/traits/triangular-epiphysis"
      }
    ],
    "genes": [
      {
        "slug": "acan",
        "symbol": "ACAN",
        "hgnc": "HGNC:319",
        "name": "aggrecan",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acan"
      },
      {
        "slug": "bmpr1b",
        "symbol": "BMPR1B",
        "hgnc": "HGNC:1077",
        "name": "bone morphogenetic protein receptor type 1B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bmpr1b"
      },
      {
        "slug": "cdc45",
        "symbol": "CDC45",
        "hgnc": "HGNC:1739",
        "name": "cell division cycle 45",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdc45"
      },
      {
        "slug": "cdc6",
        "symbol": "CDC6",
        "hgnc": "HGNC:1744",
        "name": "cell division cycle 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdc6"
      },
      {
        "slug": "cdt1",
        "symbol": "CDT1",
        "hgnc": "HGNC:24576",
        "name": "chromatin licensing and DNA replication factor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdt1"
      },
      {
        "slug": "clcn7",
        "symbol": "CLCN7",
        "hgnc": "HGNC:2025",
        "name": "Cl-/H+ antiporter 7",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/clcn7"
      },
      {
        "slug": "col9a1",
        "symbol": "COL9A1",
        "hgnc": "HGNC:2217",
        "name": "collagen type IX alpha 1 chain",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a1"
      },
      {
        "slug": "col9a2",
        "symbol": "COL9A2",
        "hgnc": "HGNC:2218",
        "name": "collagen type IX alpha 2 chain",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a2"
      },
      {
        "slug": "col9a3",
        "symbol": "COL9A3",
        "hgnc": "HGNC:2219",
        "name": "collagen type IX alpha 3 chain",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a3"
      },
      {
        "slug": "gdf5",
        "symbol": "GDF5",
        "hgnc": "HGNC:4220",
        "name": "growth differentiation factor 5",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gdf5"
      },
      {
        "slug": "gmnn",
        "symbol": "GMNN",
        "hgnc": "HGNC:17493",
        "name": "geminin DNA replication inhibitor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gmnn"
      },
      {
        "slug": "hpgd",
        "symbol": "HPGD",
        "hgnc": "HGNC:5154",
        "name": "15-hydroxyprostaglandin dehydrogenase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hpgd"
      },
      {
        "slug": "hspg2",
        "symbol": "HSPG2",
        "hgnc": "HGNC:5273",
        "name": "heparan sulfate proteoglycan 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hspg2"
      },
      {
        "slug": "inppl1",
        "symbol": "INPPL1",
        "hgnc": "HGNC:6080",
        "name": "inositol polyphosphate phosphatase like 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/inppl1"
      },
      {
        "slug": "kif1a",
        "symbol": "KIF1A",
        "hgnc": "HGNC:888",
        "name": "kinesin family member 1A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif1a"
      },
      {
        "slug": "lmbr1",
        "symbol": "LMBR1",
        "hgnc": "HGNC:13243",
        "name": "limb development membrane protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmbr1"
      },
      {
        "slug": "lonp1",
        "symbol": "LONP1",
        "hgnc": "HGNC:9479",
        "name": "lon peptidase 1, mitochondrial",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lonp1"
      },
      {
        "slug": "mmp13",
        "symbol": "MMP13",
        "hgnc": "HGNC:7159",
        "name": "matrix metallopeptidase 13",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mmp13"
      },
      {
        "slug": "mmp9",
        "symbol": "MMP9",
        "hgnc": "HGNC:7176",
        "name": "matrix metallopeptidase 9",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmp9"
      },
      {
        "slug": "orc1",
        "symbol": "ORC1",
        "hgnc": "HGNC:8487",
        "name": "origin recognition complex subunit 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/orc1"
      },
      {
        "slug": "orc4",
        "symbol": "ORC4",
        "hgnc": "HGNC:8490",
        "name": "origin recognition complex subunit 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/orc4"
      },
      {
        "slug": "orc6",
        "symbol": "ORC6",
        "hgnc": "HGNC:17151",
        "name": "origin recognition complex subunit 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/orc6"
      },
      {
        "slug": "ostm1",
        "symbol": "OSTM1",
        "hgnc": "HGNC:21652",
        "name": "osteoclastogenesis associated transmembrane protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ostm1"
      },
      {
        "slug": "pcnt",
        "symbol": "PCNT",
        "hgnc": "HGNC:16068",
        "name": "pericentrin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcnt"
      },
      {
        "slug": "pcyt1a",
        "symbol": "PCYT1A",
        "hgnc": "HGNC:8754",
        "name": "phosphate cytidylyltransferase 1A, choline",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcyt1a"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "ptpn11",
        "symbol": "PTPN11",
        "hgnc": "HGNC:9644",
        "name": "protein tyrosine phosphatase non-receptor type 11",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn11"
      },
      {
        "slug": "retreg1",
        "symbol": "RETREG1",
        "hgnc": "HGNC:25964",
        "name": "reticulophagy regulator 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/retreg1"
      },
      {
        "slug": "rmrp",
        "symbol": "RMRP",
        "hgnc": "HGNC:10031",
        "name": "RNA component of mitochondrial RNA processing endoribonuclease",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rmrp"
      },
      {
        "slug": "rnu4atac",
        "symbol": "RNU4ATAC",
        "hgnc": "HGNC:34016",
        "name": "RNA, U4atac small nuclear",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4atac"
      },
      {
        "slug": "scn9a",
        "symbol": "SCN9A",
        "hgnc": "HGNC:10597",
        "name": "sodium voltage-gated channel alpha subunit 9",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn9a"
      },
      {
        "slug": "shox",
        "symbol": "SHOX",
        "hgnc": "HGNC:10853",
        "name": "SHOX homeobox",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/shox"
      },
      {
        "slug": "slc26a2",
        "symbol": "SLC26A2",
        "hgnc": "HGNC:10994",
        "name": "solute carrier family 26 member 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc26a2"
      },
      {
        "slug": "slco2a1",
        "symbol": "SLCO2A1",
        "hgnc": "HGNC:10955",
        "name": "solute carrier organic anion transporter family member 2A1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slco2a1"
      },
      {
        "slug": "snx10",
        "symbol": "SNX10",
        "hgnc": "HGNC:14974",
        "name": "sorting nexin 10",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snx10"
      },
      {
        "slug": "tbx4",
        "symbol": "TBX4",
        "hgnc": "HGNC:11603",
        "name": "T-box transcription factor 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tbx4"
      },
      {
        "slug": "tcirg1",
        "symbol": "TCIRG1",
        "hgnc": "HGNC:11647",
        "name": "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tcirg1"
      },
      {
        "slug": "tgds",
        "symbol": "TGDS",
        "hgnc": "HGNC:20324",
        "name": "TDP-glucose 4,6-dehydratase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgds"
      },
      {
        "slug": "tnfsf11",
        "symbol": "TNFSF11",
        "hgnc": "HGNC:11926",
        "name": "TNF superfamily member 11",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfsf11"
      },
      {
        "slug": "trem2",
        "symbol": "TREM2",
        "hgnc": "HGNC:17761",
        "name": "triggering receptor expressed on myeloid cells 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trem2"
      },
      {
        "slug": "tyrobp",
        "symbol": "TYROBP",
        "hgnc": "HGNC:12449",
        "name": "transmembrane immune signaling adaptor TYROBP",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyrobp"
      },
      {
        "slug": "ufsp2",
        "symbol": "UFSP2",
        "hgnc": "HGNC:25640",
        "name": "UFM1 specific peptidase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ufsp2"
      },
      {
        "slug": "wnk1",
        "symbol": "WNK1",
        "hgnc": "HGNC:14540",
        "name": "WNK lysine deficient protein kinase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnk1"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "ddrgk1",
        "symbol": "DDRGK1",
        "hgnc": "HGNC:16110",
        "name": "DDRGK domain containing 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ddrgk1"
      },
      {
        "slug": "duox2",
        "symbol": "DUOX2",
        "hgnc": "HGNC:13273",
        "name": "dual oxidase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/duox2"
      },
      {
        "slug": "duoxa2",
        "symbol": "DUOXA2",
        "hgnc": "HGNC:32698",
        "name": "dual oxidase maturation factor 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/duoxa2"
      },
      {
        "slug": "eri1",
        "symbol": "ERI1",
        "hgnc": "HGNC:23994",
        "name": "exoribonuclease 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eri1"
      },
      {
        "slug": "hesx1",
        "symbol": "HESX1",
        "hgnc": "HGNC:4877",
        "name": "HESX homeobox 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hesx1"
      },
      {
        "slug": "idua",
        "symbol": "IDUA",
        "hgnc": "HGNC:5391",
        "name": "alpha-L-iduronidase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idua"
      },
      {
        "slug": "iyd",
        "symbol": "IYD",
        "hgnc": "HGNC:21071",
        "name": "iodotyrosine deiodinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/iyd"
      },
      {
        "slug": "lhx3",
        "symbol": "LHX3",
        "hgnc": "HGNC:6595",
        "name": "LIM homeobox 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhx3"
      },
      {
        "slug": "lhx4",
        "symbol": "LHX4",
        "hgnc": "HGNC:21734",
        "name": "LIM homeobox 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhx4"
      },
      {
        "slug": "loxl3",
        "symbol": "LOXL3",
        "hgnc": "HGNC:13869",
        "name": "lysyl oxidase like 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/loxl3"
      },
      {
        "slug": "pex7",
        "symbol": "PEX7",
        "hgnc": "HGNC:8860",
        "name": "peroxisomal biogenesis factor 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex7"
      },
      {
        "slug": "phex",
        "symbol": "PHEX",
        "hgnc": "HGNC:8918",
        "name": "phosphate regulating endopeptidase X-linked",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phex"
      },
      {
        "slug": "phyh",
        "symbol": "PHYH",
        "hgnc": "HGNC:8940",
        "name": "phytanoyl-CoA 2-hydroxylase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phyh"
      },
      {
        "slug": "pigl",
        "symbol": "PIGL",
        "hgnc": "HGNC:8966",
        "name": "phosphatidylinositol glycan anchor biosynthesis class L",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigl"
      },
      {
        "slug": "pou1f1",
        "symbol": "POU1F1",
        "hgnc": "HGNC:9210",
        "name": "POU class 1 homeobox 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pou1f1"
      },
      {
        "slug": "prop1",
        "symbol": "PROP1",
        "hgnc": "HGNC:9455",
        "name": "PROP paired-like homeobox 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prop1"
      },
      {
        "slug": "slc5a5",
        "symbol": "SLC5A5",
        "hgnc": "HGNC:11040",
        "name": "solute carrier family 5 member 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc5a5"
      },
      {
        "slug": "smad4",
        "symbol": "SMAD4",
        "hgnc": "HGNC:6770",
        "name": "SMAD family member 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smad4"
      },
      {
        "slug": "tg",
        "symbol": "TG",
        "hgnc": "HGNC:11764",
        "name": "thyroglobulin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tg"
      },
      {
        "slug": "tpo",
        "symbol": "TPO",
        "hgnc": "HGNC:12015",
        "name": "thyroid peroxidase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpo"
      },
      {
        "slug": "tshb",
        "symbol": "TSHB",
        "hgnc": "HGNC:12372",
        "name": "thyroid stimulating hormone subunit beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tshb"
      },
      {
        "slug": "fbn1",
        "symbol": "FBN1",
        "hgnc": "HGNC:3603",
        "name": "fibrillin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbn1"
      },
      {
        "slug": "flnb",
        "symbol": "FLNB",
        "hgnc": "HGNC:3755",
        "name": "filamin B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnb"
      },
      {
        "slug": "gorab",
        "symbol": "GORAB",
        "hgnc": "HGNC:25676",
        "name": "golgin, RAB6 interacting",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gorab"
      },
      {
        "slug": "ltbp3",
        "symbol": "LTBP3",
        "hgnc": "HGNC:6716",
        "name": "latent transforming growth factor beta binding protein 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ltbp3"
      },
      {
        "slug": "mafb",
        "symbol": "MAFB",
        "hgnc": "HGNC:6408",
        "name": "MAF bZIP transcription factor B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mafb"
      },
      {
        "slug": "ocrl",
        "symbol": "OCRL",
        "hgnc": "HGNC:8108",
        "name": "OCRL inositol polyphosphate-5-phosphatase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ocrl"
      },
      {
        "slug": "pex1",
        "symbol": "PEX1",
        "hgnc": "HGNC:8850",
        "name": "peroxisomal biogenesis factor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex1"
      },
      {
        "slug": "pex10",
        "symbol": "PEX10",
        "hgnc": "HGNC:8851",
        "name": "peroxisomal biogenesis factor 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex10"
      },
      {
        "slug": "pex11b",
        "symbol": "PEX11B",
        "hgnc": "HGNC:8853",
        "name": "peroxisomal biogenesis factor 11 beta",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex11b"
      },
      {
        "slug": "pex12",
        "symbol": "PEX12",
        "hgnc": "HGNC:8854",
        "name": "peroxisomal biogenesis factor 12",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex12"
      },
      {
        "slug": "pex13",
        "symbol": "PEX13",
        "hgnc": "HGNC:8855",
        "name": "peroxisomal biogenesis factor 13",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex13"
      },
      {
        "slug": "pex14",
        "symbol": "PEX14",
        "hgnc": "HGNC:8856",
        "name": "peroxisomal biogenesis factor 14",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex14"
      },
      {
        "slug": "pex16",
        "symbol": "PEX16",
        "hgnc": "HGNC:8857",
        "name": "peroxisomal biogenesis factor 16",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex16"
      },
      {
        "slug": "pex19",
        "symbol": "PEX19",
        "hgnc": "HGNC:9713",
        "name": "peroxisomal biogenesis factor 19",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex19"
      },
      {
        "slug": "pex2",
        "symbol": "PEX2",
        "hgnc": "HGNC:9717",
        "name": "peroxisomal biogenesis factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex2"
      },
      {
        "slug": "pex26",
        "symbol": "PEX26",
        "hgnc": "HGNC:22965",
        "name": "peroxisomal biogenesis factor 26",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex26"
      },
      {
        "slug": "pex3",
        "symbol": "PEX3",
        "hgnc": "HGNC:8858",
        "name": "peroxisomal biogenesis factor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex3"
      },
      {
        "slug": "pex5",
        "symbol": "PEX5",
        "hgnc": "HGNC:9719",
        "name": "peroxisomal biogenesis factor 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex5"
      },
      {
        "slug": "pex6",
        "symbol": "PEX6",
        "hgnc": "HGNC:8859",
        "name": "peroxisomal biogenesis factor 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex6"
      },
      {
        "slug": "prdm5",
        "symbol": "PRDM5",
        "hgnc": "HGNC:9349",
        "name": "PR/SET domain 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm5"
      },
      {
        "slug": "pycr1",
        "symbol": "PYCR1",
        "hgnc": "HGNC:9721",
        "name": "pyrroline-5-carboxylate reductase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pycr1"
      },
      {
        "slug": "runx2",
        "symbol": "RUNX2",
        "hgnc": "HGNC:10472",
        "name": "RUNX family transcription factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/runx2"
      },
      {
        "slug": "smarca2",
        "symbol": "SMARCA2",
        "hgnc": "HGNC:11098",
        "name": "SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smarca2"
      },
      {
        "slug": "tshr",
        "symbol": "TSHR",
        "hgnc": "HGNC:12373",
        "name": "thyroid stimulating hormone receptor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tshr"
      },
      {
        "slug": "znf469",
        "symbol": "ZNF469",
        "hgnc": "HGNC:23216",
        "name": "zinc finger protein 469",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf469"
      }
    ]
  }
}