{
  "url": "https://dantelabs.com/traits/abnormal-circulating-apolipoprotein-concentration",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-apolipoprotein-concentration",
    "id": "HP:0025201",
    "name": "Abnormal circulating apolipoprotein concentration",
    "definition": "Any deviation from the normal concentration of apolipoprotein in the blood circulation.",
    "synonyms": [
      "Abnormal apolipoprotein level"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-protein-concentration",
        "name": "Blood protein disease",
        "url": "https://dantelabs.com/traits/abnormal-circulating-protein-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "decreased-circulating-apolipoprotein-concentration",
        "name": "Decreased circulating apolipoprotein concentration",
        "genes": 0,
        "url": "https://dantelabs.com/traits/decreased-circulating-apolipoprotein-concentration"
      },
      {
        "slug": "elevated-circulating-apolipoprotein-concentration",
        "name": "Elevated circulating apolipoprotein concentration",
        "genes": 0,
        "url": "https://dantelabs.com/traits/elevated-circulating-apolipoprotein-concentration"
      }
    ],
    "genes": [
      {
        "slug": "mttp",
        "symbol": "MTTP",
        "hgnc": "HGNC:7467",
        "name": "microsomal triglyceride transfer protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mttp"
      },
      {
        "slug": "atp6v0a2",
        "symbol": "ATP6V0A2",
        "hgnc": "HGNC:18481",
        "name": "ATPase H+ transporting V0 subunit a2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v0a2"
      },
      {
        "slug": "atp6v1a",
        "symbol": "ATP6V1A",
        "hgnc": "HGNC:851",
        "name": "ATPase H+ transporting V1 subunit A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1a"
      },
      {
        "slug": "atp6v1e1",
        "symbol": "ATP6V1E1",
        "hgnc": "HGNC:857",
        "name": "ATPase H+ transporting V1 subunit E1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1e1"
      }
    ]
  }
}