{
  "url": "https://dantelabs.com/traits/unicoronal-synostosis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "unicoronal-synostosis",
    "id": "HP:0011315",
    "name": "Unicoronal synostosis",
    "definition": "Synostosis affecting only one of the coronal sutures.",
    "synonyms": [
      "Unilateral coronal suture craniosynostosis",
      "Unilateral coronal suture synostosis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "coronal-craniosynostosis",
        "name": "Coronal craniosynostosis",
        "url": "https://dantelabs.com/traits/coronal-craniosynostosis"
      }
    ],
    "narrower": [
      {
        "slug": "right-unicoronal-synostosis",
        "name": "Right unicoronal synostosis",
        "genes": 4,
        "url": "https://dantelabs.com/traits/right-unicoronal-synostosis"
      },
      {
        "slug": "left-unicoronal-synostosis",
        "name": "Left unicoronal synostosis",
        "genes": 3,
        "url": "https://dantelabs.com/traits/left-unicoronal-synostosis"
      }
    ],
    "genes": [
      {
        "slug": "smo",
        "symbol": "SMO",
        "hgnc": "HGNC:11119",
        "name": "smoothened, frizzled class receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smo"
      },
      {
        "slug": "msx2",
        "symbol": "MSX2",
        "hgnc": "HGNC:7392",
        "name": "msh homeobox 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msx2"
      },
      {
        "slug": "cep120",
        "symbol": "CEP120",
        "hgnc": "HGNC:26690",
        "name": "centrosomal protein 120",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep120"
      }
    ]
  }
}