{
  "url": "https://dantelabs.com/traits/thoracoabdominal-wall-defect",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "thoracoabdominal-wall-defect",
    "id": "HP:0100656",
    "name": "Thoracoabdominal wall defect",
    "definition": "Failure of the chest and abdominal wall to close, which is likely caused by the failure of the ventral wall to close during week 4 of development.",
    "synonyms": [
      "Thoracoabdominal schisis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abdominal-wall-defect",
        "name": "Abdominal wall defect",
        "url": "https://dantelabs.com/traits/abdominal-wall-defect"
      },
      {
        "slug": "abnormal-thorax-morphology",
        "name": "Abnormality of the chest",
        "url": "https://dantelabs.com/traits/abnormal-thorax-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      }
    ]
  }
}