{
  "url": "https://dantelabs.com/traits/sparse-or-absent-eyelashes",
  "trait": {
    "bundleId": "2026.10.21-777c9289",
    "release": "2026-09-01",
    "slug": "sparse-or-absent-eyelashes",
    "id": "HP:0200102",
    "name": "Sparse or absent eyelashes",
    "synonyms": [
      "Partial to total absence of eyelashes",
      "Sparse to absent eyelashes"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-eyelash-morphology",
        "name": "Abnormal eyelashes",
        "url": "https://dantelabs.com/traits/abnormal-eyelash-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "sparse-eyelashes",
        "name": "Sparse eyelashes",
        "genes": 80,
        "url": "https://dantelabs.com/traits/sparse-eyelashes"
      },
      {
        "slug": "absent-eyelashes",
        "name": "Absent eyelashes",
        "genes": 37,
        "url": "https://dantelabs.com/traits/absent-eyelashes"
      }
    ],
    "genes": [
      {
        "slug": "eps8l3",
        "symbol": "EPS8L3",
        "hgnc": "HGNC:21297",
        "name": "EPS8 signaling adaptor L3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eps8l3"
      },
      {
        "slug": "hr",
        "symbol": "HR",
        "hgnc": "HGNC:5172",
        "name": "HR lysine demethylase and nuclear receptor corepressor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hr"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "ripk4",
        "symbol": "RIPK4",
        "hgnc": "HGNC:496",
        "name": "receptor interacting serine/threonine kinase 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ripk4"
      },
      {
        "slug": "rpl21",
        "symbol": "RPL21",
        "hgnc": "HGNC:10313",
        "name": "ribosomal protein L21",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl21"
      },
      {
        "slug": "twist2",
        "symbol": "TWIST2",
        "hgnc": "HGNC:20670",
        "name": "twist family bHLH transcription factor 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/twist2"
      },
      {
        "slug": "zmpste24",
        "symbol": "ZMPSTE24",
        "hgnc": "HGNC:12877",
        "name": "zinc metallopeptidase STE24",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmpste24"
      },
      {
        "slug": "braf",
        "symbol": "BRAF",
        "hgnc": "HGNC:1097",
        "name": "B-Raf proto-oncogene, serine/threonine kinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/braf"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "hgnc": "HGNC:6407",
        "name": "KRas proto-oncogene, GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kras"
      },
      {
        "slug": "map2k1",
        "symbol": "MAP2K1",
        "hgnc": "HGNC:6840",
        "name": "mitogen-activated protein kinase kinase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map2k1"
      },
      {
        "slug": "map2k2",
        "symbol": "MAP2K2",
        "hgnc": "HGNC:6842",
        "name": "mitogen-activated protein kinase kinase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/map2k2"
      },
      {
        "slug": "recql4",
        "symbol": "RECQL4",
        "hgnc": "HGNC:9949",
        "name": "RecQ like helicase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql4"
      },
      {
        "slug": "tshz3",
        "symbol": "TSHZ3",
        "hgnc": "HGNC:30700",
        "name": "teashirt zinc finger homeobox 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tshz3"
      },
      {
        "slug": "anapc1",
        "symbol": "ANAPC1",
        "hgnc": "HGNC:19988",
        "name": "anaphase promoting complex subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/anapc1"
      },
      {
        "slug": "snrpe",
        "symbol": "SNRPE",
        "hgnc": "HGNC:11161",
        "name": "small nuclear ribonucleoprotein polypeptide E",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snrpe"
      }
    ]
  }
}