{
  "url": "https://dantelabs.com/traits/short-dental-root",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "short-dental-root",
    "id": "HP:0006336",
    "name": "Decreased length of dental roots",
    "label": "Short dental root",
    "definition": "Tooth root length more than 2 SD below mean, or subjectively apparently decreased tooth root length.",
    "synonyms": [
      "Decreased length of tooth roots",
      "Short dental roots",
      "Short tooth roots",
      "Underdeveloped dental roots",
      "Underdeveloped tooth roots",
      "Dental root hypoplasia",
      "Dental root hypotrophy",
      "Rhizomicry"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-size-of-the-dental-root",
        "name": "Abnormal size of the dental root",
        "url": "https://dantelabs.com/traits/abnormal-size-of-the-dental-root"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "smoc2",
        "symbol": "SMOC2",
        "hgnc": "HGNC:20323",
        "name": "SPARC related modular calcium binding 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smoc2"
      },
      {
        "slug": "ifih1",
        "symbol": "IFIH1",
        "hgnc": "HGNC:18873",
        "name": "interferon induced with helicase C domain 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifih1"
      },
      {
        "slug": "eda",
        "symbol": "EDA",
        "hgnc": "HGNC:3157",
        "name": "ectodysplasin A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eda"
      },
      {
        "slug": "edaradd",
        "symbol": "EDARADD",
        "hgnc": "HGNC:14341",
        "name": "EDAR associated via death domain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/edaradd"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "grem2",
        "symbol": "GREM2",
        "hgnc": "HGNC:17655",
        "name": "gremlin 2, DAN family BMP antagonist",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grem2"
      },
      {
        "slug": "irf6",
        "symbol": "IRF6",
        "hgnc": "HGNC:6121",
        "name": "interferon regulatory factor 6",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf6"
      },
      {
        "slug": "lrp6",
        "symbol": "LRP6",
        "hgnc": "HGNC:6698",
        "name": "LDL receptor related protein 6",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp6"
      },
      {
        "slug": "msx1",
        "symbol": "MSX1",
        "hgnc": "HGNC:7391",
        "name": "msh homeobox 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/msx1"
      },
      {
        "slug": "pax9",
        "symbol": "PAX9",
        "hgnc": "HGNC:8623",
        "name": "paired box 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax9"
      },
      {
        "slug": "sumo1",
        "symbol": "SUMO1",
        "hgnc": "HGNC:12502",
        "name": "small ubiquitin like modifier 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sumo1"
      },
      {
        "slug": "tgfa",
        "symbol": "TGFA",
        "hgnc": "HGNC:11765",
        "name": "transforming growth factor alpha",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfa"
      },
      {
        "slug": "wnt10a",
        "symbol": "WNT10A",
        "hgnc": "HGNC:13829",
        "name": "Wnt family member 10A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnt10a"
      },
      {
        "slug": "wnt10b",
        "symbol": "WNT10B",
        "hgnc": "HGNC:12775",
        "name": "Wnt family member 10B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnt10b"
      },
      {
        "slug": "kctd1",
        "symbol": "KCTD1",
        "hgnc": "HGNC:18249",
        "name": "potassium channel tetramerization domain containing 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kctd1"
      },
      {
        "slug": "tonsl",
        "symbol": "TONSL",
        "hgnc": "HGNC:7801",
        "name": "tonsoku like, DNA repair protein",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tonsl"
      },
      {
        "slug": "ssuh2",
        "symbol": "SSUH2",
        "hgnc": "HGNC:24809",
        "name": "ssu-2 homolog",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ssuh2"
      }
    ]
  }
}