{
  "url": "https://dantelabs.com/traits/setting-sun-eye-phenomenon",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "setting-sun-eye-phenomenon",
    "id": "HP:0012470",
    "name": "Setting-sun eye phenomenon",
    "definition": "An ophthalmologic sign in young children resulting from upward-gaze paresis. In this condition, the eyes appear driven downward, the sclera may be seen between the upper eyelid and the iris, and part of the lower pupil may be covered by the lower eyelid.",
    "synonyms": [
      "Eyes fixed downward",
      "Sun setting eyes",
      "Sunsetting eye"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "ophthalmoparesis",
        "name": "Weakness of muscles controlling eye movement",
        "url": "https://dantelabs.com/traits/ophthalmoparesis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cox16",
        "symbol": "COX16",
        "hgnc": "HGNC:20213",
        "name": "cytochrome c oxidase assembly factor COX16",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cox16"
      }
    ]
  }
}