{
  "url": "https://dantelabs.com/traits/renal-atrophy",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "renal-atrophy",
    "id": "HP:0012585",
    "name": "Kidney degeneration",
    "label": "Renal atrophy",
    "definition": "Atrophy of the kidney.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-renal-morphology",
        "name": "Abnormally shaped kidney",
        "url": "https://dantelabs.com/traits/abnormal-renal-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "bilateral-renal-atrophy",
        "name": "Bilateral renal atrophy",
        "genes": 1,
        "url": "https://dantelabs.com/traits/bilateral-renal-atrophy"
      },
      {
        "slug": "renal-cortical-atrophy",
        "name": "Renal cortical atrophy",
        "genes": 1,
        "url": "https://dantelabs.com/traits/renal-cortical-atrophy"
      }
    ],
    "genes": [
      {
        "slug": "alg5",
        "symbol": "ALG5",
        "hgnc": "HGNC:20266",
        "name": "ALG5 dolichyl-phosphate beta-glucosyltransferase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alg5"
      },
      {
        "slug": "dcdc2",
        "symbol": "DCDC2",
        "hgnc": "HGNC:18141",
        "name": "doublecortin domain containing 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dcdc2"
      },
      {
        "slug": "pax7",
        "symbol": "PAX7",
        "hgnc": "HGNC:8621",
        "name": "paired box 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax7"
      },
      {
        "slug": "tmem67",
        "symbol": "TMEM67",
        "hgnc": "HGNC:28396",
        "name": "transmembrane protein 67",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem67"
      },
      {
        "slug": "zmiz1",
        "symbol": "ZMIZ1",
        "hgnc": "HGNC:16493",
        "name": "zinc finger MIZ-type containing 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmiz1"
      }
    ]
  }
}