{
  "url": "https://dantelabs.com/traits/progressive-peripheral-neuropathy",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "progressive-peripheral-neuropathy",
    "id": "HP:0007133",
    "name": "Progressive peripheral neuropathy",
    "synonyms": [
      "Progressive polyneuropathy"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "peripheral-neuropathy",
        "name": "Peripheral neuropathy",
        "url": "https://dantelabs.com/traits/peripheral-neuropathy"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "coa8",
        "symbol": "COA8",
        "hgnc": "HGNC:20492",
        "name": "cytochrome c oxidase assembly factor 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/coa8"
      },
      {
        "slug": "abca1",
        "symbol": "ABCA1",
        "hgnc": "HGNC:29",
        "name": "ATP binding cassette subfamily A member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abca1"
      },
      {
        "slug": "arsa",
        "symbol": "ARSA",
        "hgnc": "HGNC:713",
        "name": "arylsulfatase A",
        "frequency": "frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/arsa"
      },
      {
        "slug": "psap",
        "symbol": "PSAP",
        "hgnc": "HGNC:9498",
        "name": "prosaposin",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/psap"
      },
      {
        "slug": "lyst",
        "symbol": "LYST",
        "hgnc": "HGNC:1968",
        "name": "lysosomal trafficking regulator",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lyst"
      }
    ]
  }
}