{
  "url": "https://dantelabs.com/traits/megaloblastic-bone-marrow",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "megaloblastic-bone-marrow",
    "id": "HP:0001980",
    "name": "Megaloblastic bone marrow",
    "definition": "Abnormal increased number of megaloblasts in the bone marrow.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-multiple-cell-lineages-in-the-bone-marrow",
        "name": "Abnormality of multiple cell lineages in the bone marrow",
        "url": "https://dantelabs.com/traits/abnormality-of-multiple-cell-lineages-in-the-bone-marrow"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "slc19a1",
        "symbol": "SLC19A1",
        "hgnc": "HGNC:10937",
        "name": "solute carrier family 19 member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc19a1"
      },
      {
        "slug": "tcn2",
        "symbol": "TCN2",
        "hgnc": "HGNC:11653",
        "name": "transcobalamin 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tcn2"
      },
      {
        "slug": "mmadhc",
        "symbol": "MMADHC",
        "hgnc": "HGNC:25221",
        "name": "metabolism of cobalamin associated D",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmadhc"
      },
      {
        "slug": "mtrr",
        "symbol": "MTRR",
        "hgnc": "HGNC:7473",
        "name": "5-methyltetrahydrofolate-homocysteine methyltransferase reductase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mtrr"
      }
    ]
  }
}