{
  "url": "https://dantelabs.com/traits/left-ventricular-diastolic-dysfunction",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "left-ventricular-diastolic-dysfunction",
    "id": "HP:0025168",
    "name": "Left ventricular diastolic dysfunction",
    "definition": "Abnormal function of the left ventricule during left ventricular relaxation and filling.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-left-ventricular-function",
        "name": "Abnormal left ventricular function",
        "url": "https://dantelabs.com/traits/abnormal-left-ventricular-function"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "alpk3",
        "symbol": "ALPK3",
        "hgnc": "HGNC:17574",
        "name": "alpha kinase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alpk3"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "prdm16",
        "symbol": "PRDM16",
        "hgnc": "HGNC:14000",
        "name": "PR/SET domain 16",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prdm16"
      },
      {
        "slug": "zmpste24",
        "symbol": "ZMPSTE24",
        "hgnc": "HGNC:12877",
        "name": "zinc metallopeptidase STE24",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zmpste24"
      },
      {
        "slug": "adamts19",
        "symbol": "ADAMTS19",
        "hgnc": "HGNC:17111",
        "name": "ADAM metallopeptidase with thrombospondin type 1 motif 19",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamts19"
      },
      {
        "slug": "flnc",
        "symbol": "FLNC",
        "hgnc": "HGNC:3756",
        "name": "filamin C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnc"
      },
      {
        "slug": "hmgcr",
        "symbol": "HMGCR",
        "hgnc": "HGNC:5006",
        "name": "3-hydroxy-3-methylglutaryl-CoA reductase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hmgcr"
      }
    ]
  }
}