{
  "url": "https://dantelabs.com/traits/immotile-sperm",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "immotile-sperm",
    "id": "HP:0012208",
    "name": "Immotile sperm",
    "definition": "A lack of mobility of ejaculated sperm.",
    "synonyms": [
      "Nonmotile sperm"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "reduced-sperm-motility",
        "name": "Reduced sperm motility",
        "url": "https://dantelabs.com/traits/reduced-sperm-motility"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ccdc39",
        "symbol": "CCDC39",
        "hgnc": "HGNC:25244",
        "name": "coiled-coil domain 39 molecular ruler complex subunit",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc39"
      },
      {
        "slug": "ccdc40",
        "symbol": "CCDC40",
        "hgnc": "HGNC:26090",
        "name": "coiled-coil domain 40 molecular ruler complex subunit",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc40"
      },
      {
        "slug": "cfap206",
        "symbol": "CFAP206",
        "hgnc": "HGNC:21405",
        "name": "cilia and flagella associated protein 206",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap206"
      },
      {
        "slug": "cfap65",
        "symbol": "CFAP65",
        "hgnc": "HGNC:25325",
        "name": "cilia and flagella associated protein 65",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap65"
      },
      {
        "slug": "cfap70",
        "symbol": "CFAP70",
        "hgnc": "HGNC:30726",
        "name": "cilia and flagella associated protein 70",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap70"
      },
      {
        "slug": "dnajb13",
        "symbol": "DNAJB13",
        "hgnc": "HGNC:30718",
        "name": "DnaJ heat shock protein family (Hsp40) member B13",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnajb13"
      },
      {
        "slug": "dzip1",
        "symbol": "DZIP1",
        "hgnc": "HGNC:20908",
        "name": "DAZ interacting zinc finger protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dzip1"
      },
      {
        "slug": "nup210l",
        "symbol": "NUP210L",
        "hgnc": "HGNC:29915",
        "name": "nucleoporin 210 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nup210l"
      },
      {
        "slug": "spink2",
        "symbol": "SPINK2",
        "hgnc": "HGNC:11245",
        "name": "serine peptidase inhibitor Kazal type 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spink2"
      },
      {
        "slug": "catsper1",
        "symbol": "CATSPER1",
        "hgnc": "HGNC:17116",
        "name": "cation channel sperm associated 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/catsper1"
      },
      {
        "slug": "catsper2",
        "symbol": "CATSPER2",
        "hgnc": "HGNC:18810",
        "name": "cation channel sperm associated 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/catsper2"
      },
      {
        "slug": "ift74",
        "symbol": "IFT74",
        "hgnc": "HGNC:21424",
        "name": "intraflagellar transport 74",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift74"
      },
      {
        "slug": "strc",
        "symbol": "STRC",
        "hgnc": "HGNC:16035",
        "name": "stereocilin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/strc"
      },
      {
        "slug": "cdc14a",
        "symbol": "CDC14A",
        "hgnc": "HGNC:1718",
        "name": "cell division cycle 14A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdc14a"
      },
      {
        "slug": "dnaaf5",
        "symbol": "DNAAF5",
        "hgnc": "HGNC:26013",
        "name": "dynein axonemal assembly factor 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnaaf5"
      },
      {
        "slug": "gas2l2",
        "symbol": "GAS2L2",
        "hgnc": "HGNC:24846",
        "name": "growth arrest specific 2 like 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gas2l2"
      },
      {
        "slug": "rsph9",
        "symbol": "RSPH9",
        "hgnc": "HGNC:21057",
        "name": "radial spoke head component 9",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rsph9"
      }
    ]
  }
}