{
  "url": "https://dantelabs.com/traits/hypothalamic-atrophy",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "hypothalamic-atrophy",
    "id": "HP:0025058",
    "name": "Hypothalamic atrophy",
    "definition": "Partial or complete wasting (loss) of hypothalamus tissue that was once present.",
    "synonyms": [
      "Atrophy of the hypothalamus"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-hypothalamus-morphology",
        "name": "Abnormal shape of hypothalamus",
        "url": "https://dantelabs.com/traits/abnormal-hypothalamus-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "spg11",
        "symbol": "SPG11",
        "hgnc": "HGNC:11226",
        "name": "SPG11 vesicle trafficking associated, spatacsin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spg11"
      }
    ]
  }
}