{
  "url": "https://dantelabs.com/traits/generalized-bone-demineralization",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "generalized-bone-demineralization",
    "id": "HP:0006462",
    "name": "Generalized bone demineralization",
    "definition": "A generalized decrease in bone mineral density.",
    "synonyms": [
      "Generalised bone demineralization"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "reduced-bone-mineral-density",
        "name": "Low solidness and mass of the bones",
        "url": "https://dantelabs.com/traits/reduced-bone-mineral-density"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ddrgk1",
        "symbol": "DDRGK1",
        "hgnc": "HGNC:16110",
        "name": "DDRGK domain containing 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ddrgk1"
      },
      {
        "slug": "chst3",
        "symbol": "CHST3",
        "hgnc": "HGNC:1971",
        "name": "carbohydrate sulfotransferase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chst3"
      }
    ]
  }
}