{
  "url": "https://dantelabs.com/traits/elevated-circulating-gaba-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "elevated-circulating-gaba-concentration",
    "id": "HP:0410053",
    "name": "Elevated circulating GABA concentration",
    "definition": "The concentration of gamma-aminobutyric acid in the blood circulation is above the upper limit of normal.",
    "synonyms": [
      "Elevated gamma-aminobutyric acid concentration",
      "Elevated gamma-aminobutyric acid level",
      "Elevated gamma-aminobutyric acid level in blood",
      "Increased circulating GABA concentration",
      "Increased gamma-aminobutyric acid concentration",
      "Increased gamma-aminobutyric acid level",
      "Increased gamma-aminobutyric acid level in blood",
      "Increased level of GABA in serum",
      "Increased level of gamma-aminobutyric acid in serum"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-gaba-concentration",
        "name": "Abnormal circulating GABA concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-gaba-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "abat",
        "symbol": "ABAT",
        "hgnc": "HGNC:23",
        "name": "4-aminobutyrate aminotransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abat"
      },
      {
        "slug": "aldh5a1",
        "symbol": "ALDH5A1",
        "hgnc": "HGNC:408",
        "name": "aldehyde dehydrogenase 5 family member A1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh5a1"
      }
    ]
  }
}