{
  "url": "https://dantelabs.com/traits/cns-foam-cells",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "cns-foam-cells",
    "id": "HP:0003640",
    "name": "CNS foam cells",
    "definition": "The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, in the central nervous system.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "foam-cells",
        "name": "Foam cells",
        "url": "https://dantelabs.com/traits/foam-cells"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "asah1",
        "symbol": "ASAH1",
        "hgnc": "HGNC:735",
        "name": "N-acylsphingosine amidohydrolase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asah1"
      },
      {
        "slug": "npc1",
        "symbol": "NPC1",
        "hgnc": "HGNC:7897",
        "name": "NPC intracellular cholesterol transporter 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npc1"
      },
      {
        "slug": "npc2",
        "symbol": "NPC2",
        "hgnc": "HGNC:14537",
        "name": "NPC intracellular cholesterol transporter 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npc2"
      }
    ]
  }
}