{
  "url": "https://dantelabs.com/traits/androgen-insufficiency",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "androgen-insufficiency",
    "id": "HP:0008226",
    "name": "Androgen insufficiency",
    "definition": "Insufficient amount of androgenic activity.",
    "synonyms": [
      "Hypoandrogenism"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "puberty-and-gonadal-disorders",
        "name": "Puberty and gonadal disorders",
        "url": "https://dantelabs.com/traits/puberty-and-gonadal-disorders"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ar",
        "symbol": "AR",
        "hgnc": "HGNC:644",
        "name": "androgen receptor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ar"
      },
      {
        "slug": "mamld1",
        "symbol": "MAMLD1",
        "hgnc": "HGNC:2568",
        "name": "mastermind like domain containing 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mamld1"
      },
      {
        "slug": "lhb",
        "symbol": "LHB",
        "hgnc": "HGNC:6584",
        "name": "luteinizing hormone subunit beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lhb"
      },
      {
        "slug": "pmfbp1",
        "symbol": "PMFBP1",
        "hgnc": "HGNC:17728",
        "name": "polyamine modulated factor 1 binding protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pmfbp1"
      },
      {
        "slug": "sun5",
        "symbol": "SUN5",
        "hgnc": "HGNC:16252",
        "name": "Sad1 and UNC84 domain containing 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sun5"
      }
    ]
  }
}