{
  "url": "https://dantelabs.com/traits/abscess",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abscess",
    "id": "HP:0025615",
    "name": "Abscess",
    "definition": "An abscess is a localized collection of purulent material surrounded by inflammation and granulation.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-immune-system-morphology",
        "name": "Abnormal immune system morphology",
        "url": "https://dantelabs.com/traits/abnormal-immune-system-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "cutaneous-abscess",
        "name": "Skin abscess",
        "genes": 13,
        "url": "https://dantelabs.com/traits/cutaneous-abscess"
      },
      {
        "slug": "liver-abscess",
        "name": "Liver abscess",
        "genes": 12,
        "url": "https://dantelabs.com/traits/liver-abscess"
      },
      {
        "slug": "peritoneal-abscess",
        "name": "Peritoneal abscess",
        "genes": 12,
        "url": "https://dantelabs.com/traits/peritoneal-abscess"
      },
      {
        "slug": "rectal-abscess",
        "name": "Rectal abscess",
        "genes": 10,
        "url": "https://dantelabs.com/traits/rectal-abscess"
      },
      {
        "slug": "tooth-abscess",
        "name": "Tooth abscess",
        "genes": 7,
        "url": "https://dantelabs.com/traits/tooth-abscess"
      },
      {
        "slug": "sterile-abscess",
        "name": "Sterile abscess",
        "genes": 5,
        "url": "https://dantelabs.com/traits/sterile-abscess"
      },
      {
        "slug": "brain-abscess",
        "name": "Brain abscess",
        "genes": 4,
        "url": "https://dantelabs.com/traits/brain-abscess"
      },
      {
        "slug": "lung-abscess",
        "name": "Lung abscess",
        "genes": 3,
        "url": "https://dantelabs.com/traits/lung-abscess"
      },
      {
        "slug": "subcutaneous-abscess",
        "name": "Subcutaneous abscess",
        "genes": 3,
        "url": "https://dantelabs.com/traits/subcutaneous-abscess"
      },
      {
        "slug": "anorectal-abscess",
        "name": "Anorectal abscess",
        "genes": 1,
        "url": "https://dantelabs.com/traits/anorectal-abscess"
      }
    ],
    "genes": [
      {
        "slug": "cybc1",
        "symbol": "CYBC1",
        "hgnc": "HGNC:28672",
        "name": "cytochrome b-245 chaperone 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cybc1"
      },
      {
        "slug": "il1rn",
        "symbol": "IL1RN",
        "hgnc": "HGNC:6000",
        "name": "interleukin 1 receptor antagonist",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il1rn"
      },
      {
        "slug": "lck",
        "symbol": "LCK",
        "hgnc": "HGNC:6524",
        "name": "LCK proto-oncogene, Src family tyrosine kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lck"
      },
      {
        "slug": "lcp2",
        "symbol": "LCP2",
        "hgnc": "HGNC:6529",
        "name": "lymphocyte cytosolic protein 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lcp2"
      },
      {
        "slug": "otulin",
        "symbol": "OTULIN",
        "hgnc": "HGNC:25118",
        "name": "OTU deubiquitinase with linear linkage specificity",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otulin"
      },
      {
        "slug": "myd88",
        "symbol": "MYD88",
        "hgnc": "HGNC:7562",
        "name": "MYD88 innate immune signal transduction adaptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myd88"
      },
      {
        "slug": "ntrk1",
        "symbol": "NTRK1",
        "hgnc": "HGNC:8031",
        "name": "neurotrophic receptor tyrosine kinase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ntrk1"
      },
      {
        "slug": "pgm3",
        "symbol": "PGM3",
        "hgnc": "HGNC:8907",
        "name": "phosphoglucomutase 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pgm3"
      },
      {
        "slug": "blm",
        "symbol": "BLM",
        "hgnc": "HGNC:1058",
        "name": "BLM RecQ like helicase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/blm"
      },
      {
        "slug": "wdr1",
        "symbol": "WDR1",
        "hgnc": "HGNC:12754",
        "name": "WD repeat domain 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr1"
      }
    ]
  }
}