{
  "url": "https://dantelabs.com/cs/genes/zmynd8",
  "gene": {
    "slug": "zmynd8",
    "symbol": "ZMYND8",
    "name": "zinc finger MYND-type containing 8",
    "hgnc": "HGNC:9397",
    "summary": null,
    "location": "20q13.12",
    "locusType": "gene with protein product",
    "aliases": [
      "RACK7",
      "KIAA1125"
    ],
    "previousSymbols": [
      "PRKCBP1"
    ],
    "ensemblId": "ENSG00000101040",
    "entrezId": 23613,
    "omim": [
      "615713"
    ],
    "uniprot": [
      "Q9ULU4"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "20",
      "start": 47209214,
      "end": 47356699,
      "strand": "-",
      "ensemblTranscript": "ENST00000471951.7",
      "refseqTranscript": "NM_001281775.3",
      "ensemblProtein": "ENSP00000420095.2",
      "refseqProtein": "NP_001268704.1",
      "exons": [
        {
          "start": 47209214,
          "end": 47210897
        },
        {
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        {
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        {
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        },
        {
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        },
        {
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        }
      ],
      "cds": {
        "start": 47210761,
        "end": 47356670
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "20",
      "start": 45837859,
      "end": 45985567,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 46782957,
      "end": 47782956,
      "genes": [
        {
          "symbol": "EYA2",
          "ensemblId": "ENSG00000064655",
          "biotype": "protein_coding",
          "start": 46894587,
          "end": 47188844,
          "strand": "+",
          "slug": "eya2"
        },
        {
          "symbol": "NCOA3",
          "ensemblId": "ENSG00000124151",
          "biotype": "protein_coding",
          "start": 47501849,
          "end": 47656877,
          "strand": "+",
          "slug": "ncoa3"
        },
        {
          "symbol": "SULF2",
          "ensemblId": "ENSG00000196562",
          "biotype": "protein_coding",
          "start": 47656197,
          "end": 47786842,
          "strand": "-",
          "slug": "sulf2"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "syndromic-complex-neurodevelopmental-disorder",
        "name": "Syndromic Complex Neurodevelopmental Disorder",
        "diseases": [
          {
            "mondoId": "MONDO:0800439",
            "name": "Syndromic Complex Neurodevelopmental Disorder",
            "genes": 23,
            "inheritance": null,
            "description": "A grouping of conditions that share developmental delay with features beyond the brain, each caused by changes in a single gene. Some of the genes here, such as ANKRD17, ASH1L and MYT1L, cause disease when one copy is changed, usually de novo; AFG2A-related disease needs changes in both copies.",
            "management": "Developmental, educational and therapy support, with assessment for seizures, growth, vision, hearing and other organ features suggested by the specific gene. Genetic counselling depends on the gene: parental testing for de novo dominant changes, and carrier testing for recessive forms.",
            "evidence": {
              "gencc": [
                "ClinGen"
              ],
              "clingen": "Definitive",
              "acmgSf": false,
              "inheritance": [
                "autosomal-dominant"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/cs/conditions/syndromic-complex-neurodevelopmental-disorder"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [
      {
        "slug": "afg2a",
        "symbol": "AFG2A",
        "name": "AAA ATPase AFG2A",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/afg2a"
      },
      {
        "slug": "ankrd17",
        "symbol": "ANKRD17",
        "name": "ankyrin repeat domain 17",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/ankrd17"
      },
      {
        "slug": "ap1s2",
        "symbol": "AP1S2",
        "name": "adaptor related protein complex 1 subunit sigma 2",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/ap1s2"
      },
      {
        "slug": "ash1l",
        "symbol": "ASH1L",
        "name": "ASH1 like histone lysine methyltransferase",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/ash1l"
      },
      {
        "slug": "brpf1",
        "symbol": "BRPF1",
        "name": "bromodomain and PHD finger containing 1",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/brpf1"
      },
      {
        "slug": "myt1l",
        "symbol": "MYT1L",
        "name": "myelin transcription factor 1 like",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/myt1l"
      },
      {
        "slug": "nfib",
        "symbol": "NFIB",
        "name": "nuclear factor I B",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/nfib"
      },
      {
        "slug": "pan2",
        "symbol": "PAN2",
        "name": "poly(A) specific ribonuclease subunit PAN2",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/pan2"
      },
      {
        "slug": "qrich1",
        "symbol": "QRICH1",
        "name": "glutamine rich 1",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/qrich1"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "name": "RNA, U4 small nuclear 2",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/rnu4-2"
      },
      {
        "slug": "setd5",
        "symbol": "SETD5",
        "name": "SET domain containing 5",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/setd5"
      },
      {
        "slug": "tbck",
        "symbol": "TBCK",
        "name": "TBC1 domain containing kinase",
        "shared": 1,
        "url": "https://dantelabs.com/cs/genes/tbck"
      }
    ],
    "sources": {
      "bundleId": "2026.10.19-9814e911",
      "panel": "2026-10-19",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}